剧情：
講述明朝女俠羅明依、錦衣衛畢正，兩人在拯救名醫李時珍時，意外穿越到現代新加坡。在重振李時珍後代的中藥事業時，化敵為友，必須攜手對抗皇宮裡任意穿越的惡勢力。在明朝的萬曆年間，女俠羅明依（黃思恬飾）企圖劫獄，救出師兄李時珍名醫（徐彬飾）。不料遇上宰相孫公公（王祿江飾）旗下的大明錦衣衛畢正（戚玉武飾）阻撓。狹路相逢，二人在一場打鬥中，卻意外穿越到了2020年的新加坡，大開眼界。巧合的是，兩人遇到李時珍的後代，李濟世（徐彬分飾）。李濟世一家有一間五十年聲譽的藥膳餐廳仙草堂，但是昔日輝煌不再，生意每況愈下。明依誓言要讓仙草堂重振雄風，濟世答應幫他們搞清楚穿越的方法，畢正一心只想回到明朝，只好答應幫忙他。在兩人的幫助下，仙草堂生意蒸蒸日上。好景不長，突然一日，二人被電流打中，一時間，又穿越回到了大明。他們穿越到現代的秘密，被邪惡的孫公公和龔王（徐鳴傑飾）發現了。這兩個野心家要來現代尋找鄭和留下的寶藏，以購買強大兵器，霸占大明。明依是否能及時阻止？畢正是否會忠誠於孫公公，還是和明依站在同一陣線上？雙俠的故事將如何收場？
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